Ontology highlight
ABSTRACT:
SUBMITTER: Lee U
PROVIDER: S-EPMC5523016 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Molecules and cells 20170614 6
The primary cilium is a non-motile microtubule-based organelle that protrudes from the surface of most human cells and works as a cellular antenna to accept extracellular signals. Primary cilia assemble from the basal body during the resting stage (G<sub>0</sub> phase) and simultaneously disassemble with cell cycle re-entry. Defective control of assembly or disassembly causes diverse human diseases including ciliopathy and cancer. To identify the effective compounds for studying primary cilium d ...[more]