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Pulse Wave Velocity Predicts Response to Renal Denervation in Isolated Systolic Hypertension.


ABSTRACT: Renal sympathetic denervation seems to be less effective as a treatment for hypertension in patients with isolated systolic hypertension, a condition associated with elevated central arterial stiffness. Because isolated systolic hypertension can also be caused by wave reflection or increased cardiac output, a more differentiated approach might improve patient preselection for renal sympathetic denervation. We sought to evaluate the additional predictive value of invasive pulse wave velocity for response to renal sympathetic denervation in patients with combined versus isolated systolic hypertension. Patients scheduled for renal sympathetic denervation underwent additional invasive measurement of pulse wave velocity and pulse pressure before denervation. Blood pressure was assessed via ambu

SUBMITTER: Fengler K 

PROVIDER: S-EPMC5524114 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature