Comparative effectiveness of anticoagulation on midterm infrainguinal bypass graft patency.

ABSTRACT:

Objective

Therapeutic anticoagulation (AC) is used clinically for prolongation of infrainguinal bypass patency, but evidence for the efficacy of this practice is conflicting. The objective of our study was to determine the association of AC with bypass graft primary patency.

Methods

Clinical and comorbid data of patients undergoing infrainguinal bypass grafts to a below-knee target with at least 1 year of follow-up performed from 2003 to 2015 were obtained from the Society for Vascular Surgery Vascular Quality Initiative. Inverse propensity of treatment-weighted Cox regression was used to assess the effect of AC on patency in the total cohort while adjusting for clinical, operative, and comorbid differences between treatment groups. Subgroup analyses of distal targets and co

SUBMITTER: Liang NL 

PROVIDER: S-EPMC5524600 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature