Fertility Preservation in Endometriosis Patients: Anti-Mullerian Hormone Is a Reliable Marker of the Ovarian Follicle Density.

ABSTRACT:

Objective

To analyze the ovarian reserve via measurement of follicular density and anti-Müllerian hormone (AMH) in endometriosis patients participating to a clinical program of cortical ovarian cryopreservation.

Design

Retrospective analysis of serum AMH levels and prospective investigation of ovarian follicle number.

Setting

University Hospital.

Patients

Two hundred and two women with endometriosis and 400 controls.

Interventions

Blood samples and ovarian biopsies.

Main outcome measures

Correlation of serum AMH levels and the number of non-growing follicles in the biopsied cortical tissues in endometriosis and control subjects, including age, type of AMH kit, and the laboratory performing the analysis as covariates.

Results

AMH leve

SUBMITTER: Garavaglia E 

PROVIDER: S-EPMC5524724 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature