Visibiome: an efficient microbiome search engine based on a scalable, distributed architecture.

ABSTRACT:

Background

Given the current influx of 16S rRNA profiles of microbiota samples, it is conceivable that large amounts of them eventually are available for search, comparison and contextualization with respect to novel samples. This process facilitates the identification of similar compositional features in microbiota elsewhere and therefore can help to understand driving factors for microbial community assembly.

Results

We present Visibiome, a microbiome search engine that can perform exhaustive, phylogeny based similarity search and contextualization of user-provided samples against a comprehensive dataset of 16S rRNA profiles environments, while tackling several computational challenges. In order to scale to high demands, we developed a distributed system that combines web

SUBMITTER: Azman SK 

PROVIDER: S-EPMC5525214 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature