Long-Term Outcomes of Children With Trisomy 13 and 18 After Congenital Heart Disease Interventions.

ABSTRACT:

Background

The purpose of this study is to report short- and long-term outcomes after congenital heart defect (CHD) interventions in patients with trisomy 13 or 18.

Methods

A retrospective review of the Pediatric Cardiac Care Consortium (PCCC) identified children with trisomy 13 or 18 with interventions for CHD between 1982 and 2008. Long-term survival and cause of death were obtained through linkage with the National Death Index.

Results

A total of 50 patients with trisomy 13 and 121 patients with trisomy 18 were enrolled in PCCC between 1982 and 2008; among them 29 patients with trisomy 13 and 69 patients with trisomy 18 underwent intervention for CHD. In-hospital mortality rates for patients with trisomy 13 or trisomy 18 were 27.6% and 13%, respectively. Causes of

SUBMITTER: Peterson JK 

PROVIDER: S-EPMC5526352 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature