Pupil adaptation corresponds to quantitative measures of autism traits in children.

ABSTRACT: The pupil is known to reflect a range of psychological and physiological variables, including cognitive effort, arousal, attention, and even learning. Within autism spectrum disorder (ASD), some work has used pupil physiology to successfully classify patients with or without autism. As we have come to understand the heterogeneity of ASD and other neurodevelopmental disorders, the relationship between quantitative traits and physiological markers has become increasingly more important, as this may lead us closer to the underlying biological basis for atypical responses and behaviors. We implemented a novel paradigm designed to capture patterns of pupil adaptation during sustained periods of dark and light conditions in a pediatric sample that varied in intellectual ability and clinical feat

SUBMITTER: DiCriscio AS 

PROVIDER: S-EPMC5526922 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature