Design, Analysis and Testing of a Novel Mitral Valve for Transcatheter Implantation.

ABSTRACT: Mitral regurgitation is a common mitral valve dysfunction which may lead to heart failure. Because of the rapid aging of the population, conventional surgical repair and replacement of the pathological valve are often unsuitable for about half of symptomatic patients, who are judged high-risk. Transcatheter valve implantation could represent an effective solution. However, currently available aortic valve devices are inapt for the mitral position. This paper presents the design, development and hydrodynamic assessment of a novel bi-leaflet mitral valve suitable for transcatheter implantation. The device consists of two leaflets and a sealing component made from bovine pericardium, supported by a self-expanding wireframe made from superelastic NiTi alloy. A parametric design procedure based

SUBMITTER: Bozkurt S 

PROVIDER: S-EPMC5527080 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature