Adaptive molecular evolution of MC1R gene reveals the evidence for positive diversifying selection in indigenous goat populations.

ABSTRACT: Detecting signatures of selection can provide a new insight into the mechanism of contemporary breeding and artificial selection and further reveal the causal genes associated to the phenotypic variation. However, the signatures of selection on genes entailing for profitable traits between Chinese commercial and indigenous goats have been poorly interpreted. We noticed footprints of positive selection at MC1R gene containing SNPs genotyped in five Chinese native goat breeds. An experimental distribution of F_ST was built based on approximations of F_ST for each SNP across five breeds. We identified selection using the high F_ST outlier method and found that MC1R candidate gene show evidence of positive selection. Furthermore,

SUBMITTER: Ahmad HI 

PROVIDER: S-EPMC5528238 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature