The Impact on Central Blood Pressure and Arterial Stiffness Post Renal Denervation in Patients With Stage 3 and 4 Chronic Kidney Disease: The Prairie Renal Denervation Study.

ABSTRACT:

Background

Central aortic blood pressures and arterial stiffness are better indicators of cardiovascular outcomes than brachial blood pressures. However, their response to renal denervation (RDN) in patients with stage 3 and stage 4 chronic kidney disease (CKD) has not yet been examined.

Objective

To evaluate the impact of RDN on central blood pressures, brachial (office and ambulatory) blood pressures, arterial stiffness, glomerular filtration rate (GFR), 24-hour urine protein, and selective cardiac parameters observed on echocardiograms.

Design

Single-center, single-arm with pre-RDN/post-RDN follow-up.

Setting

Patients are being recruited from the multidisciplinary CKD clinic.

Patients

Fifty consecutive patients with stage 3 or stage 4 CKD and resistan

SUBMITTER: Prasad B 

PROVIDER: S-EPMC5528937 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature