Coronary heart disease and risk factors as predictors of trajectories of psychological distress from midlife to old age.

ABSTRACT:

Objective

To examine coronary heart disease (CHD) and its risk factors as predictors of long-term trajectories of psychological distress from midlife to old age.

Methods

In the Whitehall II cohort study, 6890 participants (4814 men, 2076 women; mean age 49.5 years) had up to seven repeat assessments of psychological distress over 21 years (mean follow-up 19 years). CHD and its risk factors (lifestyle-related risk factors, diabetes, hypertension and cholesterol) were assessed at baseline. Group-based trajectory modelling was used to identify clusters of individuals with a similar pattern of psychological distress over time.

Results

We identified four trajectories of psychological distress over the follow-up: 'persistently low' (69% of the participants), 'persistently i

SUBMITTER: Virtanen M 

PROVIDER: S-EPMC5529979 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature