High-intensity flywheel exercise and recovery of atrophy after 90 days bed--rest.

ABSTRACT:

Aims

To investigate differential muscle atrophy during bed-rest, the impact of a high-intensity concentric-eccentric (flywheel) resistance exercise countermeasure and muscle recovery after bed-rest.

Methods

Twenty-five healthy male subjects underwent 90 dayshead-down tilt bed-rest. Volume of individual lower-limb muscles was measured via MRI before, twice during and four times up to 1 year after bed-rest. Subjects were either inactive (n=16) or performed flywheel exercise every third day of bed-rest (n=9). Functional performance was assessed via countermovement jump.

Results

On 'intent-to-treat' analysis, flywheel prevented atrophy in the vasti (p<0.001) and reduced atrophy in the hip adductor/extensor adductor magnus (p=0.001) and ankle dorsiflexors/toe flexors (sole

SUBMITTER: Belavy DL 

PROVIDER: S-EPMC5530106 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature