Differences in sensitivity to microstructure between cyclic- and impact-based microindentation of human cortical bone.

ABSTRACT: Unlike the known relationships between traditional mechanical properties and microstructural features of bone, the factors that influence the mechanical resistance of bone to cyclic reference point microindention (cRPI) and impact microindention (IMI) have yet to be identified. To determine whether cRPI and IMI properties depend on microstructure, we indented the tibia mid-shaft, the distal radius, and the proximal humerus from 10 elderly donors using the BioDent and OsteoProbe (neighboring sites). As the only output measure of IMI, bone material strength index (BMSi) was significantly different across all three anatomical sites being highest for the tibia mid-shaft and lowest for the proximal humerus. Total indentation distance (inverse of BMSi) was higher for the proximal humerus than fo

SUBMITTER: Uppuganti S 

PROVIDER: S-EPMC5530367 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature