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Acute coronary syndrome and acute kidney injury: role of inflammation in worsening renal function.


ABSTRACT:

Background

Acute Kidney Injury (AKI), a common complication of acute coronary syndromes (ACS), is associated with higher mortality and longer hospital stays. The role of cytokines and other mediators is unknown in AKI induced by an ACS (ACS-AKI), leading to several unanswered questions. The worsening of renal function is usually seen as a dichotomous phenomenon instead of a dynamic change, so evaluating changes of the renal function in time may provide valuable information in the ACS-AKI setting. The aim of this study was to explore inflammatory factors associated to de novo kidney injury induced by de novo cardiac injury secondary to ACS.

Methods

One hundred four consecutive patients with ACS were initially included on the time of admission to the Coronary Unit of the Insti

SUBMITTER: Ortega-Hernandez J 

PROVIDER: S-EPMC5530514 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature