Antibody trapping: A novel mechanism of parasite immune evasion by the trematode Echinostoma caproni.

ABSTRACT:

Background

Helminth infections are among the most prevalent neglected tropical diseases, causing an enormous impact in global health and the socioeconomic growth of developing countries. In this context, the study of helminth biology, with emphasis on host-parasite interactions, appears as a promising approach for developing new tools to prevent and control these infections.

Methods/principal findings

The role that antibody responses have on helminth infections is still not well understood. To go in depth into this issue, work on the intestinal helminth Echinostoma caproni (Trematoda: Echinostomatidae) has been undertaken. Adult parasites were recovered from infected mice and cultured in vitro. Double indirect immunofluorescence at increasing culture times was done to show t

SUBMITTER: Cortes A 

PROVIDER: S-EPMC5531663 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature