Risk Factors for Intensive Care Unit Admission in Patients with Autoimmune Encephalitis.

ABSTRACT:

Background

Prevention and early recognition of critical illness in patients with autoimmune encephalitis (AE) is essential to achieve better outcome.

Aim of the study

To evaluate risk factors for intensive care unit (ICU) admission and its prognostic impact in patients with AE.

Patients and methods

A reclassification of patients hospitalized between 2011 and 2016 revealed 17 "definite" and 15 "probable" AE cases. Thirteen patients (41%) developed critical illness and required ICU admission. The underlying conditions were intractable seizures or status epilepticus (54%), altered mental state (39%), and respiratory failure (8%).

Results

ICU admission was associated with longer time from first symptoms to hospitalization (p = 0.046). Regression analysis rev

SUBMITTER: Harutyunyan G 

PROVIDER: S-EPMC5532517 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature