Long-term exposure to residential ambient fine and coarse particulate matter and incident hypertension in post-menopausal women.

ABSTRACT:

Background

Long-term exposure to ambient particulate matter (PM) has been previously linked with higher risk of cardiovascular events. This association may be mediated, at least partly, by increasing the risk of incident hypertension, a key determinant of cardiovascular risk. However, whether long-term exposure to PM is associated with incident hypertension remains unclear.

Methods

Using national geostatistical models incorporating geographic covariates and spatial smoothing, we estimated annual average concentrations of residential fine (PM_2.5), respirable (PM₁₀), and course (PM_10-2.5) fractions of particulate matter among 44,255 post-menopausal women free of hypertension enrolled in the Women's Health Initiative (WHI) clinical trials. We us

SUBMITTER: Honda T 

PROVIDER: S-EPMC5532534 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature