Multiscale adaptive analysis of circadian rhythms and intradaily variability: Application to actigraphy time series in acute insomnia subjects.

ABSTRACT: Circadian rhythms become less dominant and less regular with chronic-degenerative disease, such that to accurately assess these pathological conditions it is important to quantify not only periodic characteristics but also more irregular aspects of the corresponding time series. Novel data-adaptive techniques, such as singular spectrum analysis (SSA), allow for the decomposition of experimental time series, in a model-free way, into a trend, quasiperiodic components and noise fluctuations. We compared SSA with the traditional techniques of cosinor analysis and intradaily variability using 1-week continuous actigraphy data in young adults with acute insomnia and healthy age-matched controls. The findings suggest a small but significant delay in circadian components in the subjects with acut

SUBMITTER: Fossion R 

PROVIDER: S-EPMC5533453 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature