Treatment Precedes Positive Symptoms in North American Adolescent and Young Adult Clinical High Risk Cohort.

ABSTRACT: Early intervention for psychotic disorders, a growing international priority, typically targets help-seeking populations with emerging psychotic ("positive") symptoms. We assessed the nature of and degree to which treatment of individuals at high risk for psychosis preceded or followed the onset of positive symptoms. The North American Prodrome Longitudinal Study-2 collected psychosocial treatment histories for 745 (98%) of 764 high-risk participants (M age = 18.9, 57% male, 57.5% Caucasian, 19.1% Hispanic) recruited from 8 North American communities. Similar to prior findings, 82% of participants reported psychosocial treatment prior to baseline assessment, albeit with significant variability across sites (71%-96%). Participants first received treatment a median of 1.7 years prior to the

SUBMITTER: Woodberry KA 

PROVIDER: S-EPMC5533647 | biostudies-literature | 2018 Jan-Feb

REPOSITORIES: biostudies-literature