Episodic memory functions in first episode psychosis and clinical high risk individuals.

ABSTRACT:

Objective

Individuals with schizophrenia have disproportionate memory impairments when encoding relational versus item-specific information, and when using recollection versus familiarity during retrieval. It is unclear whether this pattern is unique to people with chronic schizophrenia, or if it occurs in individuals after a first episode of psychosis (FE), or when at clinical high-risk for psychosis (CHR).

Methods

We administered the Relational and Item-Specific Memory task (RiSE) to 22 CHR, 101 FE, and 58 typically developing (TD) participants. We examined group differences in item and relational encoding, and familiarity-based and recollection-based retrieval using parametric analysis and structural equation modeling (SEM). Longitudinal data allowed us to examine relatio

SUBMITTER: Greenland-White SE 

PROVIDER: S-EPMC5533652 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature