Male chromosomal polymorphisms reduce cumulative live birth rate for IVF couples.

ABSTRACT:

Purpose

Chromosomal polymorphisms are associated with infertility, but their effects on assisted reproductive outcomes are still quite conflicting, especially after IVF treatment. This study evaluated the role of chromosomal polymorphisms of different genders in IVF pregnancy outcomes.

Methods

Four hundred and twenty-five infertile couples undergoing IVF treatment were divided into three groups: 214 couples with normal chromosomes (group A, control group), 86 couples with female polymorphisms (group B), and 125 couples with male polymorphisms (group C). The pregnancy outcomes after the first and cumulative transfer cycles were analyzed, and the main outcome measures were live birth rate (LBR) after the first transfer cycle and cumulative LBR after a complete IVF cycle.

Re

SUBMITTER: Ni T 

PROVIDER: S-EPMC5533681 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature