Genetic variation and population structure of Botswana populations as identified with AmpFLSTR Identifiler short tandem repeat (STR) loci.

ABSTRACT: Population structure was investigated in 990 Botswana individuals according to ethno-linguistics, Bantu and Khoisan, and geography (the nine administrative districts) using the Identifiler autosomal microsatellite markers. Genetic diversity and forensic parameters were calculated for the overall population, and according to ethno-linguistics and geography. The overall combined power of exclusion (CPE) was 0.9999965412 and the combined match probability 6,28 × 10^-19. CPE was highest for the Khoisan Tuu ethnolinguistic group and the Northeast District at 0.9999582029 and 0.9999922652 respectively. CMP ranged from 6.28 × 10^-19 (Khoisan Tuu) to 1,02 × 10^-18 (Northwest district). Using pairwise genetic distances (F_ST), analysis of molecular variance (

SUBMITTER: Tau T 

PROVIDER: S-EPMC5533702 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature