Sensory integration deficits support a dimensional view of psychosis and are not limited to schizophrenia.

ABSTRACT: Visual dysfunction is commonplace in schizophrenia and occurs alongside cognitive, psychotic and affective symptoms of the disorder. Psychophysical evidence suggests that this dysfunction results from impairments in the integration of low-level neural signals into complex cortical representations, which may also be associated with symptom formation. Despite the symptoms of schizophrenia occurring in a range of disorders, the integration deficit has not been tested in broader patient populations. Moreover, it remains unclear whether such deficits generalize across other sensory modalities. The present study assessed patients with a range of psychotic and nonpsychotic disorders and healthy controls on visual contrast detection, visual motion integration, auditory tone detection and auditory

SUBMITTER: Carter O 

PROVIDER: S-EPMC5534945 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature