The house spider genome reveals an ancient whole-genome duplication during arachnid evolution.

ABSTRACT:

Background

The duplication of genes can occur through various mechanisms and is thought to make a major contribution to the evolutionary diversification of organisms. There is increasing evidence for a large-scale duplication of genes in some chelicerate lineages including two rounds of whole genome duplication (WGD) in horseshoe crabs. To investigate this further, we sequenced and analyzed the genome of the common house spider Parasteatoda tepidariorum.

Results

We found pervasive duplication of both coding and non-coding genes in this spider, including two clusters of Hox genes. Analysis of synteny conservation across the P. tepidariorum genome suggests that there has been an ancient WGD in spiders. Comparison with the genomes of other chelicerates, including that of the ne

SUBMITTER: Schwager EE 

PROVIDER: S-EPMC5535294 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature