Application of the Stage, Size, Grade, and Necrosis (SSIGN) Score for Clear Cell Renal Cell Carcinoma in Contemporary Patients.

ABSTRACT:

Background

The tumor stage, size, grade, and necrosis (SSIGN) score was originally defined using patients treated with radical nephrectomy (RN) between 1970 and 1998 for clear cell renal cell carcinoma (ccRCC), excluding patients treated with partial nephrectomy (PN).

Objective

To characterize the original SSIGN score cohort with longer follow-up and evaluate a contemporary series of patients treated with RN and PN.

Design, setting, and participants

Retrospective single-institution review of 3600 consecutive surgically treated ccRCC patients grouped into three cohorts: original RN, contemporary (1999-2010) RN, and contemporary PN.

Intervention

RN or PN.

Outcome measurements and statistical analysis

The association of the SSIGN score with risk of death fr

SUBMITTER: Parker WP 

PROVIDER: S-EPMC5536178 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature