The influence of serum uric acid on renal function in patients with calcium or uric acid stone: A population-based analysis.

ABSTRACT:

Objectives

To determine the influence of serum uric acid (UA) levels on renal impairment in patients with UA stone.

Materials and methods

We retrospectively analyzed 463 patients with calcium oxalate and/or calcium phosphate stones (CaOx/CaP), and 139 patients with UA stones. The subjects were divided into the serum UA-high (UA ≥ 7.0 mg/dL) or the UA-low group (UA < 7.0 mg/dL). The control group comprised 3082 community-dwelling individuals that were pair-matched according to age, sex, body mass index, comorbidities, hemoglobin, serum albumin, and serum UA using propensity score matching. We compared renal function between controls and patients with UA stone (analysis 1), and between patients with CaOx/CaP and with UA stone (analysis 2). Logistic regression analysis was used

SUBMITTER: Tanaka Y 

PROVIDER: S-EPMC5536286 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature