High-flow nasal oxygen therapy and noninvasive ventilation in the management of acute hypoxemic respiratory failure.

ABSTRACT: High-flow nasal cannula (HFNC) oxygen therapy is a recent technique delivering a high flow of heated and humidified gas. HFNC is simpler to use and apply than noninvasive ventilation (NIV) and appears to be a good alternative treatment for hypoxemic acute respiratory failure (ARF). HFNC is better tolerated than NIV, delivers high fraction of inspired oxygen (FiO₂), generates a low level of positive pressure and provides washout of dead space in the upper airways, thereby improving mechanical pulmonary properties and unloading inspiratory muscles during ARF. A recent multicenter randomized controlled trial showed benefits of HFNC concerning mortality and intubation in severe patients with hypoxemic ARF. In management of patients with hypoxemic ARF, NIV results have been conflicti

SUBMITTER: Frat JP 

PROVIDER: S-EPMC5537116 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature