Commonly used medications and endometrial cancer survival: a population-based cohort study.

ABSTRACT:

Background

Increasing incidence and new indications for existing drugs make it important to identify new adjuvant therapies for endometrial cancer (EC).

Methods

This is a prospective cohort study of 3058 newly diagnosed EC cases from 1998 to 2010, identified through record linkages between the UK Clinical Practice Research Datalink, the National Cancer Research Datalink and death registrations from the Office of National Statistics. Using Cox regression models, unadjusted and adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated for EC-specific survival.

Results

Over a mean 6.1 (range 1-16) years of follow-up, there were 394 EC-specific deaths. There was no evidence of a significant association between post-diagnostic use of statins (adjusted

SUBMITTER: Sanni OB 

PROVIDER: S-EPMC5537503 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature