Sex differences in intracerebral hemorrhage expansion and mortality.

ABSTRACT:

Background and objective

Due to conflicting results in multiple studies, uncertainty remains regarding sex differences in severity and mortality after intracerebral hemorrhage (ICH). We investigated the impact of sex on ICH severity, expansion, and mortality.

Methods

We analyzed prospectively collected ICH patients and assessed clinical variables and mortality rate. Mediation analyses were used to examine associations between sex and mortality and sex and hematoma expansion.

Results

2212 patients were investigated, 53.5% male. Men with ICH were younger (72 vs. 77years), had greater smoking and alcohol use, and were more likely to have hypertension, diabetes, hypercholesterolemia and coronary artery disease (all p<0.05). Lobar hemorrhages were more frequent in women (4

SUBMITTER: Marini S 

PROVIDER: S-EPMC5538146 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature