Morphology of Dbx1 respiratory neurons in the preBotzinger complex and reticular formation of neonatal mice.

ABSTRACT: The relationship between neuron morphology and function is a perennial issue in neuroscience. Information about synaptic integration, network connectivity, and the specific roles of neuronal subpopulations can be obtained through morphological analysis of key neurons within a microcircuit. Here we present morphologies of two classes of brainstem respiratory neurons. First, interneurons derived from Dbx1-expressing precursors (Dbx1 neurons) in the preBötzinger complex (preBötC) of the ventral medulla that generate the rhythm for inspiratory breathing movements. Second, Dbx1 neurons of the intermediate reticular formation that influence the motor pattern of pharyngeal and lingual movements during the inspiratory phase of the breathing cycle. We describe the image acquisition and subsequent d

SUBMITTER: Akins VT 

PROVIDER: S-EPMC5538238 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature