GenomeVIP: a cloud platform for genomic variant discovery and interpretation.

ABSTRACT: Identifying genomic variants is a fundamental first step toward the understanding of the role of inherited and acquired variation in disease. The accelerating growth in the corpus of sequencing data that underpins such analysis is making the data-download bottleneck more evident, placing substantial burdens on the research community to keep pace. As a result, the search for alternative approaches to the traditional "download and analyze" paradigm on local computing resources has led to a rapidly growing demand for cloud-computing solutions for genomics analysis. Here, we introduce the Genome Variant Investigation Platform (GenomeVIP), an open-source framework for performing genomics variant discovery and annotation using cloud- or local high-performance computing infrastructure. GenomeVIP

SUBMITTER: Mashl RJ 

PROVIDER: S-EPMC5538560 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature