Risk factors for adverse drug reactions in pediatric inpatients: A cohort study.

ABSTRACT:

Purpose

The present study aims to identify the risk factors for adverse drug reactions (ADR) in pediatric inpatients.

Methods

A prospective cohort study in one general pediatric ward in a hospital in Northeast Brazil was conducted in two stages: the first stage was conducted between August 17th and November 6th, 2015, and the second one between March 1st and August 25th, 2016. We included children aged 0-14 years 11 months hospitalized with a minimum stay of 48 hours. Observed outcomes were the ADR occurrence and the time until the first ADR observed. In the univariate analysis, the time to the first ADR was compared among groups using a log-rank test. For the multivariate analysis, the Cox regression model was used.

Results

A total of 173 children (208 admissions) an

SUBMITTER: Andrade PHS 

PROVIDER: S-EPMC5538648 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature