Attention impairments and ADHD symptoms in adult narcoleptic patients with and without hypocretin deficiency.

ABSTRACT:

Background

Attentional complaints are common in narcolepsy patients and can overlap with daytime sleepiness features. Few studies attempted to characterize attentional domains in narcolepsy leading to controversial results. We aimed to assess the impact of hypocretin deficiency on attentional functioning by comparing performances on the attention network test (ANT) of narcoleptic patients with hypocretin deficiency (narcolepsy type 1-NT1) versus patients without hypocretin deficiency (narcolepsy type 2-NT2) and healthy controls. We also addressed frequency and severity of psychopathological symptoms and their influence on performances on ANT.

Methods

Twenty-one NT1 patients, fifteen NT2 patients and twenty-two healthy controls underwent the ANT, which allows assessing three

SUBMITTER: Filardi M 

PROVIDER: S-EPMC5538711 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature