Spatiotemporal regulation of nervous system development in the annelid Capitella teleta.

ABSTRACT:

Background

How nervous systems evolved remains an unresolved question. Previous studies in vertebrates and arthropods revealed that homologous genes regulate important neurogenic processes such as cell proliferation and differentiation. However, the mechanisms through which such homologs regulate neurogenesis across different bilaterian clades are variable, making inferences about nervous system evolution difficult. A better understanding of neurogenesis in the third major bilaterian clade, Spiralia, would greatly contribute to our ability to deduce the ancestral mechanism of neurogenesis.

Results

Using whole-mount in situ hybridization, we examined spatiotemporal gene expression for homologs of soxB, musashi, prospero, achaete-scute, ne

SUBMITTER: Sur A 

PROVIDER: S-EPMC5539756 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature