Morphologic Accuracy in Differentiating Primary Lung Adenocarcinoma From Squamous Cell Carcinoma in Cytology Specimens.

ABSTRACT:

Context

-The National Cancer Care Network and the combined College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology guidelines indicate that all lung adenocarcinomas (ADCs) should be tested for epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements. As the majority of patients present at a later stage, the subclassification and molecular analysis must be done on cytologic material.

Objective

-To evaluate the accuracy and interobserver variability among cytopathologists in subtyping non-small cell lung carcinoma using cytologic preparations.

Design

-Nine cytopathologists from different institutions submitted cases of non-small cell lung carcinoma with surgi

SUBMITTER: Zakowski MF 

PROVIDER: S-EPMC5539947 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature