A proteomic insight into the midgut proteome of Ornithodoros moubata females reveals novel information on blood digestion in argasid ticks.

ABSTRACT:

Background

The argasid tick Ornithodoros moubata is the main African vector of the human relapsing fever agent Borrelia duttoni and the African swine fever virus. Together with saliva, the tick midgut forms part of the host-tick-pathogen interface, and numerous midgut proteins play key functions in the blood digestion-related process and the infection and transmission of pathogens. This work explores the composition of the midgut proteome of unfed and fed O. moubata females with the aim to complete the biological information already obtained from the midgut transcriptome and provide a more robust and comprehensive perspective of this biological system.

Methods

Midgut tissues taken from females before feeding and 48 h after feeding were subjected to LC/MS-MS analysis. After f

SUBMITTER: Oleaga A 

PROVIDER: S-EPMC5540513 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature