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Refining the Policy for Timing of Kidney Transplant Waitlist Qualification.


ABSTRACT:

Background

Earlier qualification for the kidney transplant waitlist expedites transplant and is therefore associated with improved outcomes. U.S. Organ Procurement and Transplantation Network policies state that "measured or calculated creatinine clearance or glomerular filtration rate less than or equal to 20 mL/min" triggers waitlist time accrual. The choice of qualification method is somewhat arbitrary, and the policy implies that decline in renal function is monotonic.

Methods

(1) We used survival analysis to quantify temporal differences in waitlist qualification by applying 3 kidney-function-estimating equations (Cockcroft-Gault, Modification of Diet in Renal Disease study, Chronic Kidney Disease Epidemiology Collaboration) to serial creatinine measurements from 3 pati

SUBMITTER: Lee BJ 

PROVIDER: S-EPMC5540633 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature