On the detection of high frequency correlations in resting state fMRI.

ABSTRACT: Current studies of resting-state connectivity rely on coherent signal fluctuations at frequencies below 0.1 Hz, however, recent studies using high-speed fMRI have shown that fluctuations above 0.5 Hz may exist. This study replicates the feasibility of measuring high frequency (HF) correlations in six healthy controls and a patient with a brain tumor while analyzing non-physiological signal sources via simulation. Resting-state data were acquired using a high-speed multi-slab echo-volumar imaging pulse sequence with 136 ms temporal resolution. Bandpass frequency filtering in combination with sliding window seed-based connectivity analysis using running mean of the correlation maps was employed to map HF correlations up to 3.7 Hz. Computer simulations of Rician noise and the underlying point

SUBMITTER: Trapp C 

PROVIDER: S-EPMC5540810 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature