Associations between human breast milk hormones and adipocytokines and infant growth and body composition in the first 6 months of life.

ABSTRACT:

Background

Much is to be learnt about human breast milk (HBM).

Objectives

The purpose of this study is to extend our knowledge of HBM by investigating the role of maternal body mass index (BMI), sex and stage of lactation (month 1 vs. 6) on HBM insulin, glucose, leptin, IL-6 and TNF-α and their associations with infant body composition.

Methods

Thirty-seven exclusively breastfeeding infants (n = 37; 16♀, 21♂), and their mothers (19-47 kg m^-2 ) were studied at 1 and 6 months of lactation. Infants had body composition measured (using dual-energy X-ray absorptiometry) and HBM collected.

Results

A significant interaction between maternal BMI and infant sex on insulin levels (p = 0.0322) was observed such that insulin was 229% higher in obese mothers nurs

SUBMITTER: Fields DA 

PROVIDER: S-EPMC5540830 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature