Interaction of ACE genotype and salt intake on hypertension among Chinese Kazakhs: results from a population-based cross-sectional study.

ABSTRACT:

Objectives

To explore the effect of interaction between ACE genotype and salt intake on hypertension among Chinese Kazakhs, and to compare applications of interactions between logistic model and generalised partially linear tree-based regression (GPLTR) model.

Design

Population-based cross-sectional study.

Setting

Hong Dun, North Xinjiang, China.

Participants

Non-consanguineous Chinese Kazakh participants (n=916, 342 men and 574 women) aged ≥30 years.

Main outcome measures

Association between ACE genotype and hypertension, association between salt intake and hypertension, and interaction of ACE genotype and salt intake on hypertension in two models.

Results

Associations between salt intake and hypertension were different in ACE genotype of II and

SUBMITTER: Wang Y 

PROVIDER: S-EPMC5541444 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature