TranslatiOnal Registry for CardiomyopatHies (TORCH) - rationale and first results.

ABSTRACT:

Aims

Non-ischemic cardiomyopathies (CMPs) comprise heart muscle disorders of different causes with high variability in disease phenotypes and clinical progression. The lack of national structures for the efficient recruitment, clinical and molecular classification, and follow-up of patients with non-ischemic CMPs limit the thorough analysis of disease mechanisms and the evaluation of novel diagnostic and therapeutic strategies. This paper describes a national, prospective, multicenter registry for patients with non-ischemic CMPs. The main objective of this registry is to create a central hub for clinical outcome studies, a joint resource for diagnostic and therapeutic trials, a common biomaterial bank, and a resource for detailed molecular analyses utilizing patients' biomaterials.

SUBMITTER: Seyler C 

PROVIDER: S-EPMC5542726 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature