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Thyroid homeostasis in mother-child pairs in relation to maternal iodine status: the MISA study.


ABSTRACT:

Background/objectives

Iodine deficiency during pregnancy may influence maternal and foetal thyroid function with the risk of causing neurocognitive and psychomotor deficits in the offspring. The objective of this study was to assess iodine status in pregnant women from Northern Norway and to investigate the influence of iodine status on maternal and infant thyroid function.

Subjects/methods

Women from the Northern Norway Mother-and-Child contaminant Cohort Study (MISA) donated a blood and urine sample at three visits during their pregnancy and postpartum period (in second trimester, 3 days and 6 weeks after delivery. N=197). Women were assigned to iodine status groups according to urine iodine concentrations (UICs) in second trimester and mixed effects linear models were use

SUBMITTER: Berg V 

PROVIDER: S-EPMC5543254 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature