Clinicopathologic, Immunohistochemical, and Molecular Features of Histiocytoid Sweet Syndrome.

ABSTRACT:

Importance

Histiocytoid Sweet syndrome is a rare histopathologic variant of Sweet syndrome. The nature of the histiocytoid infiltrate has generated considerable controversy in the literature.

Objective

The main goal of this study was to conduct a comprehensive overview of the immunohistochemical phenotype of the infiltrate in histiocytoid Sweet syndrome. We also analyze whether this variant of Sweet syndrome is more frequently associated with hematologic malignancies than classic Sweet syndrome.

Design

This is a retrospective case series study of the clinicopathologic, immunohistochemical, and molecular features of 33 patients with a clinicopathologic diagnosis of histiocytoid Sweet syndrome was conducted in the dermatology departments of 5 university hospitals and a

SUBMITTER: Alegria-Landa V 

PROVIDER: S-EPMC5543327 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature