Physiology-based regularization of the electrocardiographic inverse problem.

ABSTRACT: The inverse problem of electrocardiography aims at noninvasively reconstructing electrical activity of the heart from recorded body-surface electrocardiograms. A crucial step is regularization, which deals with ill-posedness of the problem by imposing constraints on the possible solutions. We developed a regularization method that includes electrophysiological input. Body-surface potentials are recorded and a computed tomography scan is performed to obtain the torso-heart geometry. Propagating waveforms originating from several positions at the heart are simulated and used to generate a set of basis vectors representing spatial distributions of potentials on the heart surface. The real heart-surface potentials are then reconstructed from the recorded body-surface potentials by finding a sp

SUBMITTER: Cluitmans MJM 

PROVIDER: S-EPMC5544815 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature