Ion channels and ion selectivity.

ABSTRACT: Specific macromolecular transport systems, ion channels and pumps, provide the pathways to facilitate and control the passage of ions across the lipid membrane. Ion channels provide energetically favourable passage for ions to diffuse rapidly and passively according to their electrochemical potential. Selective ion channels are essential for the excitability of biological membranes: the action potential is a transient phenomenon that reflects the rapid opening and closing of voltage-dependent Na⁺-selective and K⁺-selective channels. One of the most critical functional aspects of K⁺ channels is their ability to remain highly selective for K⁺ over Na⁺ while allowing high-throughput ion conduction at a rate close to the diffusion limit. P

SUBMITTER: Roux B 

PROVIDER: S-EPMC5544903 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature