Development of an algorithm using clinical tests to avoid post-operative residual neuromuscular block.

ABSTRACT:

Background

Quantitative neuromuscular monitoring is the gold standard to detect postoperative residual curarization (PORC). Many anesthesiologists, however, use insensitive, qualitative neuromuscular monitoring or unreliable, clinical tests. Goal of this multicentre, prospective, double-blinded, assessor controlled study was to develop an algorithm of muscle function tests to identify PORC.

Methods

After extubation a blinded anesthetist performed eight clinical tests in 165 patients. Test results were correlated to calibrated electromyography train-of-four (TOF) ratio and to a postoperatively applied uncalibrated acceleromyography. A classification and regression tree (CART) was calculated developing the algorithm to identify PORC. This was validated against uncalibrated acc

SUBMITTER: Unterbuchner C 

PROVIDER: S-EPMC5545011 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature