Effects of Weight Loss with and without Exercise on Regional Body Fat Distribution in Postmenopausal Women.

ABSTRACT:

Background/aims

The purpose was to determine whether lifestyle interventions have different effects on regional fat in women with normal glucose tolerance vs. impaired glucose tolerance (NGT vs. IGT).

Methods

Changes in glucose metabolism (2-h oral glucose-tolerance tests), android to gynoid fat mass ratio (dual energy X-ray absorptiometry [DXA]), visceral to subcutaneous abdominal fat area ratio (CT), and abdominal to gluteal subcutaneous fat cell weight (FCW; adipose tissue biopsies) were determined in 60 overweight postmenopausal women (45-80 years) following 6 months of weight loss alone (WL; n = 28) or with aerobic exercise (AEX + WL; n = 32).

Results

The interventions led to ∼8% decrease in weight, but only the AEX + WL group improved fitness (↑11% in VO2max) an

SUBMITTER: Serra MC 

PROVIDER: S-EPMC5545797 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature