Clinical practice variation and need for pediatric-specific treatment guidelines among rheumatologists caring for children with ANCA-associated vasculitis: an international clinician survey.

ABSTRACT:

Background

Because pediatric antineutrophil cytoplasmic antibody-associated vasculitis is rare, management generally relies on adult data. We assessed treatment practices, uptake of existing clinical assessment tools, and interest in pediatric treatment protocols among rheumatologists caring for children with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA).

Methods

A needs-assessment survey developed by an international working group of pediatric rheumatologists and two nephrologists was circulated internationally. Data were summarized with descriptive statistics. Pearson's chi-square tests were used in inferential univariate analyses.

Results

The 209 respondents from 36 countries had collectively seen ~1600 children with GPA/MPA; 144 had see

SUBMITTER: Westwell-Roper C 

PROVIDER: S-EPMC5545848 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature