Altered brain structural networks in attention deficit/hyperactivity disorder children revealed by cortical thickness.

ABSTRACT: This study investigated the cortical thickness and topological features of human brain anatomical networks related to attention deficit/hyperactivity disorder. Data were collected from 40 attention deficit/hyperactivity disorder children and 40 normal control children. Interregional correlation matrices were established by calculating the correlations of cortical thickness between all pairs of cortical regions (68 regions) of the whole brain. Further thresholds were applied to create binary matrices to construct a series of undirected and unweighted graphs, and global, local, and nodal efficiencies were computed as a function of the network cost. These experimental results revealed abnormal cortical thickness and correlations in attention deficit/hyperactivity disorder, and showed that the

SUBMITTER: Liu T 

PROVIDER: S-EPMC5546518 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature