Driven translocation of a semi-flexible polymer through a nanopore.

ABSTRACT: We study the driven translocation of a semi-flexible polymer through a nanopore by means of a modified version of the iso-flux tension propagation theory, and extensive molecular dynamics (MD) simulations. We show that in contrast to fully flexible chains, for semi-flexible polymers with a finite persistence length [Formula: see text] the trans side friction must be explicitly taken into account to properly describe the translocation process. In addition, the scaling of the end-to-end distance R _N as a function of the chain length N must be known. To this end, we first derive a semi-analytic scaling form for R _N, which reproduces the limits of a rod, an ideal chain, and an excluded volume chain in the appropriate limits. We then quantitatively characterize the nature

SUBMITTER: Sarabadani J 

PROVIDER: S-EPMC5547125 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature